Posts Tagged by cataract
|December 14, 2014||Posted by admin under 2014, Abstract, cataract, news, Pharmacology|
VANCOUVER, BC — Statin therapy significantly elevates the risk of developing cataracts severe enough to warrant surgery, suggests analyses of two distinct cohorts, one from Canada and another from the US, that add to a hazy landscape of prior studies variously concluding for or against such a risk for the widely used drugs.
For now, the possibility of such a risk from statins and its potential mechanisms should be explored in prospective trials, “especially in light of increased statin use for primary prevention of cardiovascular disease and the importance of acceptable vision in old age, when cardiovascular disease is common,” according to the report, published in the December 2014 issue of the Canadian Journal of Cardiology with lead author Dr Stephanie J Wise (University of British Columbia, Vancouver).
“However, because the relative risk is low and because cataract surgery is (more…) (328)
|December 6, 2014||Posted by admin under 2014, cataract, Pharmacology, vitreo-retina|
NEW YORK (Reuters Health) – The nonsteroidal anti-inflammatory eyedrops ketorolac and nepafenac do not prevent cystoid macular edema after phacoemulsification, researchers from Brazil report.
Most patients exhibit inflammation after cataract surgery that requires treatment with an anti-inflammatory eyedrop, typically a steroid, they write in the British Journal of Ophthalmology, online November 10.
Dr. Patrick Frensel Tzelikis from Brasilia Ophthalmologic Hospital in Brasilia and colleagues evaluated the effects of ophthalmic solutions of ketorolac 0.4% and nepafenac 0.1% in preventing cystic macular edema (assessed by optical coherence tomography (OCT)) after phacoemulsification cataract extraction.
Patients were randomly assigned to receive an artificial tear substitute (n=40), ketorolac 0.4% (n=45) or nepafenac 0.1% (n=41). All patients received prednisolone 1% eyedrops on a (more…) (574)
|December 4, 2014||Posted by admin under 2014, Abstract, cataract, Information, Pharmacology|
CHICAGO — A tapered-release dexamethasone punctum plug appears to be a reasonable alternative to medicated eye drops for patients who have undergone cataract surgery, according to early research.
“In clinical use, the sustained release may reduce patient pain,” said Tom Walters, MD, from Texan Eye in Austin. Dr Walters presented the phase 2 study during the cataracts session here at the American Academy of Ophthalmology 2014 Annual Meeting.
The prospective randomized double-masked trial involved 59 patients at 4 sites. The primary end points of the study were the absence of cells in the anterior chamber — a measure of ocular inflammation — and the absence of pain.
Immediately after cataract surgery, patients were randomized; half received the dexamethasone punctum plug and half received a placebo vehicle punctum plug. In this study, (more…) (427)
|November 2, 2014||Posted by admin under 2014, Abstract, cataract|
This retrospective study evaluated the safety of intracameral moxifloxacin 0.5% (500 mg/0.1 ml) in 244 patients (353 eyes) who underwent uncomplicated cataract surgery. At three months postop, there was minimal anterior chamber reaction, and no significant change was noted in corneal thickness or endothelial cell density.
Philippine Journal of Ophthalmology, January-June 2014 (400)
|August 14, 2014||Posted by admin under 2014, Abstract, cataract, IOL|
Using an experimental model for calculating induced stress on corneal incisions during intraocular lens implantation, researchers compared the nozzles of common injectors using two incision sizes, 2.4- or 2.2-mm. They showed major differences (greater than 38%) between the lowest and highest levels of induced stress when different injectors and different incision sizes were compared. They suggest that better surgical results may be achieved if surgeons match the injector with the incision size. If the surgeon prefers a specific injector system, the incision size should be matched to the size of the injector’s nozzle.
American Journal of Ophthalmology, July 2014
|August 12, 2014||Posted by admin under 2014, Adenexa & Conjunctiva, cataract|
This randomized, controlled, double-masked trial evaluated two preop sterilization techniques: In one group (153 eyes), the lid margin was compressed and scrubbed for 360 degrees five times with a dry sterile cotton-tipped applicator immediately after ocular sterilization and before povidone–iodine irrigation of the conjunctival sac. The second group (153 eyes) had identical sterilization but no lid scrubbing. The rate of positive bacterial culture in liquid in the collecting bag was significantly higher with mechanical compression of the lid margin (P=.001), perhaps due to secretions from the lid margin glands.
Journal of Cataract & Refractive Surgery, August 2014 (1505)
|August 11, 2014||Posted by admin under 2014, Abstract, cataract, IOL|
This is the first study to use Humphrey Visual Field 10-2 testing to compare the effects of multifocal and monofocal IOLs on the central 10 degrees of vision. The multifocal group demonstrated a significant depression in MD, by approximately 2 dB, that did not improve with time or neuroadaptation. The authors suggest multifocal IOLs may be inadvisable in patients who cannot tolerate central visual field reduction, such as those with macular degeneration, retinal pigment epithelium changes or glaucoma.
American Journal of Ophthalmology, August 2014
|December 9, 2013||Posted by admin under 2013, cataract, Glaucoma|
The CyPass Micro-Stent procedure for glaucoma can be safely combined with cataract surgery, according to 2-year results from the CYCLE trial. Investigators report that the procedure provided sustained control of intraocular pressure and reduced medication use.
“This procedure is an attempt to have surgeries for glaucoma that are safer and easier for the patient,” said investigator Brian Flowers, MD, from Fort Worth, Texas. “Current surgical treatments for glaucoma are associated with events such as suprachoroidal hemorrhage and bleb-related complications. Microinvasive surgical stenting of the supraciliary space may improve aqueous flow, with fewer complications,” he explained here at the American Academy of Ophthalmology (AAO) 2013 Annual Meeting.
There are 2 main approaches to minimally invasive glaucoma surgery, (more…) (1472)
|November 25, 2013||Posted by admin under 2013, Abstract, Surgery|
BACKGROUND Virtual simulators have been widely implemented in medical and surgical training, including ophthalmology. The increasing number of published articles in this field mandates a review of the available results to assess current technology and explore future opportunities.
METHOD A PubMed search was conducted and a total of 10 articles were reviewed.
RESULTS Virtual simulators have shown construct validity in many modules, successfully differentiating user experience levels during simulated phacoemulsification surgery. Simulators have also shown improvements in wet-lab performance. The implementation of simulators in the residency training has been associated with a decrease in cataract surgery complication rates.
CONCLUSIONS Virtual reality simulators are an effective tool in measuring performance and differentiating trainee skill level. Additionally, they may be useful in improving surgical skill and patient outcomes in cataract surgery. Future opportunities rely on taking advantage of technical improvements in simulators for education and research. (692)
|November 20, 2013||Posted by admin under 2013, aao, cataract, Conferences|
Even in the hands of experts, not all cataract surgeries go as planned, as attendees at a “Spotlight on Cataract Complications” session found out during the second day of the American Academy of Ophthalmology meeting here in New Orleans. Session co-chair David F. Chang, MD, said the key is to remain calm.
“Don’t panic—take a deep breath,” he said, adding that even unwelcome events during surgery can result in good visual outcomes.
For instance, if there is a break in the anterior capsule, (more…) (2317)