|December 10, 2013||Posted by admin under Glaucoma, Pharmacology|
Author(s): Vandewalle E, Abegão Pinto L, Van Bergen T, Spielberg L, Fieuws S, Moons L, Spileers W, Zeyen T, Stalmans I
Treatments discussed: bevacizumab
AIMS To investigate the efficacy and safety of a single intracameral bevacizumab injection to improve the outcome of trabeculectomy.
METHODS A 12-month, prospective, randomised, double-masked, placebo-controlled trial. Patients with medically uncontrolled open-angle glaucoma scheduled for a primary trabeculectomy were recruited and randomised to receive 50 µL of either bevacizumab (1.25 mg) or placebo (balanced salt solution) peroperatively. Absolute success was defined as intraocular pressure (IOP) ≤18 mm Hg and>5 mm Hg with at least 30% reduction from baseline and no loss of light perception. (more…)
|December 10, 2013||Posted by admin under Abstract, peadiatric, Pharmacology|
Author(s): Kiryazov K, Stefova M, Iotova V
Treatments discussed: brimonidine, brinzolamide, timolol
Topical ocular medications have been widely prescribed and successfully used in children for the management of different ophthalmic disorders. We present 2 infants admitted to our pediatric intensive care unit who developed altered state of consciousness, hypotonia, hypothermia, bradycardia, and apnea after instillation of ophthalmic drops. The second infant also had (more…)
|December 9, 2013||Posted by admin under 2013, cataract, Glaucoma|
The CyPass Micro-Stent procedure for glaucoma can be safely combined with cataract surgery, according to 2-year results from the CYCLE trial. Investigators report that the procedure provided sustained control of intraocular pressure and reduced medication use.
“This procedure is an attempt to have surgeries for glaucoma that are safer and easier for the patient,” said investigator Brian Flowers, MD, from Fort Worth, Texas. “Current surgical treatments for glaucoma are associated with events such as suprachoroidal hemorrhage and bleb-related complications. Microinvasive surgical stenting of the supraciliary space may improve aqueous flow, with fewer complications,” he explained here at the American Academy of Ophthalmology (AAO) 2013 Annual Meeting.
There are 2 main approaches to minimally invasive glaucoma surgery, (more…)
|December 8, 2013||Posted by admin under aao, Cornea|
Rho kinase inhibitor eyedrops stimulate the growth of corneal epithelium, according to a preliminary study in patients with Fuchs dystrophy.
“Think outside the box,” said Shigeru Kinoshita, MD, from Kyoto Prefectural University of Japan. The drops, also known as rock inhibitors, could become a treatment reality in the future. “This is just the beginning,” Dr. Kinoshita said. “We may be heading toward minimally invasive surgery for Fuchs dystrophy and other forms of corneal problems.”
Dr. Kinoshita and his team pioneered the technique as part of research on new therapies for corneal endothelial diseases, as well as for the early stages of Fuchs dystrophy. The first approach is aimed at using cultivated corneal endothelial cells plus a rock inhibitor to promote cell adhesion, proliferation, and inhibition of apoptosis of corneal endothelial cells.
The second effort — to develop a novel medical treatment (more…)
|December 6, 2013||Posted by admin under 2013, Abstract, Glaucoma|
Taking oral contraceptives for more than 3 years doubles a woman’s risk for glaucoma, according to a large population-based study.
“This study is the first to document this risk, and it’s important for the general population,” said lead investigator Ye Elaine Wang, MD, from the University of California at San Francisco. “Postmenopausal women should be reassured that the study does not prove causative effects, but women who have used oral contraceptives for 3 years or more and who have additional risk factors for glaucoma should be checked annually for the disease during their eye exams.”
Dr. Wang presented the findings here at the American Academy of Ophthalmology 2013 Annual Meeting.
Known risk factors for glaucoma include age, race, family history of glaucoma, elevated intraocular pressure, and existing visual field defects.
The cross-sectional study was based on 3406 (more…)
|December 4, 2013||Posted by admin under 2013, news, Pharmacology, vitreo-retina|
Patients with central serous choroidopathy treated with nonsteroidal anti-inflammatory drug (NSAID) eyedrops recover faster than when they are not treated, according to a new study.
“We found that we could cut the average time to resolution by 50% with the NSAID eyedrops, which is the way we have been treating patients in our own practice,” said Michael Singer, MD, from Medical Center Ophthalmology in San Antonio.
He presented the results here at the American Academy of Ophthalmology 2013 Annual Meeting.
Central serous choroidopathy is characterized by spontaneous serous detachment of the neurosensory retina in the macular region, with or without retinal pigment epithelium detachment. Its cause is not known, but one theory suggests that increased (more…)
|November 28, 2013||Posted by admin under 2013, cataract, Surgery, Video|
Oval Capsulorhexis : Dr Kiranjit Singh (With Narration by Prof Dr Daljit Singh)
|November 27, 2013||Posted by admin under 2013, Abstract, Optics & Refraction|
Defocus Incorporated Soft Contact (DISC) lens slows myopia progression in Hong Kong Chinese schoolchildren: a 2-year randomised clinical trial Lam C, Tang W, Tse D, Tang Y, To C; British Journal of Ophthalmology (BJO) (Oct 2013)
AIMS To determine if ‘Defocus Incorporated Soft Contact’ (DISC) lens wear slows childhood myopia progression.
METHODS A 2-year double-blind randomised controlled trial was carried out in 221 children aged 8-13 years, with myopia between -1.00 and -5.00 Dioptres (D) and astigmatism ≤1.00 D. Subjects were randomly assigned to the DISC (n=111) or single vision (SV; n=110) contact lens group. DISC lenses incorporated concentric rings, which provided an addition of +2.50 D, alternating with the normal distance correction. Refractive error (cycloplegic autorefraction) and (more…)
|November 25, 2013||Posted by admin under 2013, Abstract, Surgery|
BACKGROUND Virtual simulators have been widely implemented in medical and surgical training, including ophthalmology. The increasing number of published articles in this field mandates a review of the available results to assess current technology and explore future opportunities.
METHOD A PubMed search was conducted and a total of 10 articles were reviewed.
RESULTS Virtual simulators have shown construct validity in many modules, successfully differentiating user experience levels during simulated phacoemulsification surgery. Simulators have also shown improvements in wet-lab performance. The implementation of simulators in the residency training has been associated with a decrease in cataract surgery complication rates.
CONCLUSIONS Virtual reality simulators are an effective tool in measuring performance and differentiating trainee skill level. Additionally, they may be useful in improving surgical skill and patient outcomes in cataract surgery. Future opportunities rely on taking advantage of technical improvements in simulators for education and research.