|May 3, 2013||Posted by admin under 2012, Abstract, cataract|
Multifocal IOLs may affect assessment of common eye diseases
Investigators evaluated the influence of a diffractive multifocal IOL on standard automated perimetry (SAP) size III and size V test results. Patients had a clinically relevant reduction of visual sensitivity, manifested by a mean 2dB decrease in mean deviation on Humphrey visual field testing, compared to patients with monofocal IOLs and phakic controls. They conclude this reduction interferes with the assessment of common eye diseases such as glaucoma and comes on top of the decline of visual sensitivity due to normal aging or age-related eye diseases.
JAMA Ophthalmology, April 2012 (318)
|May 2, 2013||Posted by admin under 2013, Abstract, cataract, Glaucoma, Pharmacology|
Diclofenac appears equivalent to dexamethasone for combined phacotrab with MMC
This prospective, double-masked clinical trial included 42 patients with glaucoma and cataract randomized to postop treatment with topical diclofenac sodium 0.1% or topical dexamethasone phosphate 0.1%. At 12 months, diclofenac was shown to be at least as good as the topical steroid. Investigators noted a trend toward a clinical advantage with diclofenac sodium 0.1%, the most potent NSAID, as patients exhibited a clinical tendency to do better than the dexamethasone group in terms of the number of glaucoma medications, IOP and bleb morphology.
Journal of Glaucoma, March 2013 (355)
|May 1, 2013||Posted by admin under 2011, Abstract, cataract|
Pseudophakic monovision may offer better intermediate vision than multifocal IOLs
Researchers prospectively compared visual function and patient satisfaction in 21 patients implanted with bilateral diffractive multifocal IOLs (AcrySof ReSTOR SN60D3) and 22 patients with monofocal IOL monovision (AcrySof SN60WF). Visual exam at three months showed bilateral uncorrected distance vision and near vision were slightly better in the multifocal group, but the difference was not statistically different. Monovision patients had significantly better intermediate vision and less difficulty using computers without glasses. Monovision patients also had a slightly higher overall satisfaction score and significantly fewer complaints of glare and halos.
Journal of Cataract & Refractive Surgery, March 2011 (260)
|April 30, 2013||Posted by admin under 2013, Abstract, Conjunctiva, Cornea|
OSSN-associated pterygia appears uncommon
This retrospective study evaluated the prevalence of ocular surface squamous neoplasia (OSSN) in surgically excised pterygia in a multiple-physician practice in South Florida. With a prevalence of 1.7 percent, this study supports the theory that UV radiation is involved in the pathophysiology of OSSN. Prognosis was excellent when treated with wide surgical margins and cryotherapy. The recurrence rates for unexpected OSSN with pterygia were comparable to those for isolated OSSN, highlighting the need for vigilant and long-term follow-up.
Ophthalmology, March 2013 (376)
|April 29, 2013||Posted by admin under 2013, Abstract, Glaucoma, Neuro-ophthalmology|
ONH parameters symmetrical in healthy patients
Using data from the Blue Mountains Eye Study, investigators assessed the symmetry of optic nerve head (ONH) parameters measured by the Heidelberg Retina Tomograph 3 (HRT 3) between fellow eyes in a normal elderly population. There was minimal interocular difference and substantial interocular correlation in ONH parameters. A difference of 0.2 was found to be the cut-off limit for normals. They conclude that the diagnosis of glaucoma using asymmetry analysis might receive a greater contribution from cup-to-disc area ratio than vertical cup-to-disc ratio, as the former parameter has the highest symmetry in healthy eyes.
American Journal of Ophthalmology, March 2013 (396)
|April 28, 2013||Posted by admin under 2013, Abstract, cataract, Surgery|
Iris retractors may increase risk of posterior capsule staining
Investigators report five cases of inadvertent posterior capsule staining with trypan blue during phacoemulsification. They conclude this complication can occur in eyes without a history of trauma or any known zonular pathology. Additionally, they found that iris retractors may increase the risk of posterior capsule staining by allowing the posterior flow of trypan blue under the iris and through the zonules to the posterior capsule, resulting in poor visualization during surgery.
American Journal of Ophthalmology, April 2013 (307)
|April 27, 2013||Posted by admin under 2013, Abstract, Cornea|
Femtosecond-assisted intrastromal arcuate keratotomy shows promise
This prospective case series evaluated the feasibility and safety of purely intrastromal arcuate keratotomy procedures performed with a femtosecond laser without penetrating Bowman’s layer or Descemet’s membrane. In 16 eyes treated for minor to medium preoperative corneal astigmatism (range 0.75 to 3.00 D), a mean reduction of 76.6 percent in absolute refractive astigmatism was achieved at six months. Patients also showed a significant improvement in manifest and topographic cylinder as well as an improvement in UDVA. No perforations occurred, no overcorrections occurred, and all incisions were placed at planned locations.
Journal of Cataract & Refractive Surgery, April 2013 (386)
|April 26, 2013||Posted by admin under 2013, Abstract, vitreo-retina|
Longer axial length may be protective against diabetic retinopathy
This literature review evaluated the potential mechanisms, both refractive and structural, by which myopia protects against diabetic retinopathy. Longer axial length was the only variable consistently associated with a lower risk and severity of diabetic retinopathy in patients with myopia. The authors speculate that the decrease in blood flow and/or increase in ocular volume associated with increased axial length may be the mechanism for this protective effect.
Clinical and Experimental Ophthalmology, April 2013 (215)
|April 25, 2013||Posted by admin under 2013, Abstract, vitreo-retina|
Beta-blockers may reduce anti-VEGF treatment burden
This retrospective case series study included 46 patients with wet AMD treated with bevacizumab injections on a prn regime. Patients treated with systemic beta-adrenergic blocking agents required less intravitreal injections (5.2 vs. 7.9), a statistically significant difference (P= 0.0068, multiple linear regression).
Retina, April 2013 (349)
|April 24, 2013||Posted by admin under 2013, Abstract, Glaucoma|
Researchers compared the amount of IOP asymmetry in a large group of ethnically diverse patients with and without glaucoma to determine the probability of having primary open-angle glaucoma at each level of IOP asymmetry. Patients with an IOP difference of ≥6mm Hg should be considered at great risk for having glaucoma, while those with symmetric pressures are not likely to have the disease. As a diagnostic consideration, the value of asymmetry should be weighted heavily in patients who show consistent IOP asymmetry on repeat clinic visits.
Journal of Glaucoma, March 2012 (313)