|December 4, 2013||Posted by admin under 2013, news, Pharmacology, vitreo-retina|
Patients with central serous choroidopathy treated with nonsteroidal anti-inflammatory drug (NSAID) eyedrops recover faster than when they are not treated, according to a new study.
“We found that we could cut the average time to resolution by 50% with the NSAID eyedrops, which is the way we have been treating patients in our own practice,” said Michael Singer, MD, from Medical Center Ophthalmology in San Antonio.
He presented the results here at the American Academy of Ophthalmology 2013 Annual Meeting.
Central serous choroidopathy is characterized by spontaneous serous detachment of the neurosensory retina in the macular region, with or without retinal pigment epithelium detachment. Its cause is not known, but one theory suggests that increased (more…) (183)
|November 15, 2013||Posted by admin under 2013, news, vitreo-retina|
First large population-based study investigating long-term risks supports need for ophthalmologic follow-up of children and adults born before 32 weeks of gestation
SAN FRANCISCO – Nov. 7, 2013 – Children born extremely prematurely have up to a 19 times greater risk of retinal detachment later in life than peers born at term, according to a Swedish study published this month in Ophthalmology, the journal of the American Academy of Ophthalmology. In the first large population-based, long-term investigation of the association between preterm birth and later retinal detachment, (more…) (733)
|June 7, 2013||Posted by admin under 2013, vitreo-retina|
Anti-VEGFs possibly linked to increased heart attack risk
This large retrospective study examined health records from Western Australian eye clinics to determine the risk of thromboembolic and gastrointestinal bleeding events in the 12 months after injections of bevacizumab or ranibizumab, compared with photodynamic therapy and untreated community controls. Though all adverse events were rare, anti-VEGF-treated patients were 2.3 times more likely to have a heart attack compared with controls. There was no difference in adverse events between bevacizumab and ranibizumab (1.6 and 2.1 events/100 persons, respectively). It’s unclear if the increased risk is associated with AMD itself or anti-VEGF treatment.
Retina, June 2013
|May 23, 2013||Posted by admin under 2012, cataract, vitreo-retina|
Delayed-onset endophthalmitis associated with better visual outcomes
This large retrospective series included all patients treated for culture-proven endophthalmitis after cataract surgery at a single university center between 2000 and 2009. Patients with delayed-onset endophthalmitis (>6 weeks after surgery) generally presented with better initial visual acuities, had a lower frequency of hypopyon, and better visual outcomes compared to acute-onset patients (≤6 weeks after surgery). Propionibacterium acnes and coagulase-negative Staphylococcus species were the most common organisms cultured in both groups and were associated with the best visual acuity outcomes in both groups.
American Journal of Ophthalmology, March 2012 (363)
|May 19, 2013||Posted by admin under cataract, IOL, Video, vitreo-retina|
No-assistant technique for glued IOL : Dr Priya Narang MS
An excellent demo video using animation and real surgery videos to explain the tricky concepts in general and the no-assistant technique in particular. (380)
|May 16, 2013||Posted by admin under Pharmacology, vitreo-retina|
AREDS formula requires tinkering
Five-year results from the AREDS2 study shows that adding lutein and zeaxanthin, and/or omega-3 fatty acids to the original AREDS formula did not further reduce the risk of AMD progression. However, they found some benefit in two subgroups: Subjects who took an AREDS formulation with lutein and zeaxanthin but no beta-carotene cut their risk by about 18 percent, while those who had very little lutein and zeaxanthin in their diets but took an AREDS formulation with lutein and zeaxanthin were about 25 percent less likely to develop advanced AMD compared with participants with similar dietary intake who did not take lutein and zeaxanthin. The authors recommend a new formula consisting of 400 IU of vitamin E, 500 mg vitamin C, 10 mg lutein and 2 mg zeaxanthin, 80 mg zinc and 2 mg copper.
Journal of the American Medical Association, May 5 2013 (185)
|May 8, 2013||Posted by admin under 2013, Abstract, vitreo-retina|
Short-term external buckle shows promise for retinal detachment
This retrospective case series reports two-year outcomes in 31 patients (33 eyes) with a rhegmatogenous retinal detachment with inferior retinal breaks. The external buckle consisted of a 505 sponge sutured along the blunt side of a 279 tyre. It was deeply embedded into the inferior fornix without suture after pneumatic retinopexy. The buckle remained in place for three days. Twenty-nine eyes achieved successful reattachment within six months with no more treatment. While the procedure failed in four eyes, reattachment was achieved with further treatment.
American Journal of Ophthalmology, April 2013 (206)
|April 26, 2013||Posted by admin under 2013, Abstract, vitreo-retina|
Longer axial length may be protective against diabetic retinopathy
This literature review evaluated the potential mechanisms, both refractive and structural, by which myopia protects against diabetic retinopathy. Longer axial length was the only variable consistently associated with a lower risk and severity of diabetic retinopathy in patients with myopia. The authors speculate that the decrease in blood flow and/or increase in ocular volume associated with increased axial length may be the mechanism for this protective effect.
Clinical and Experimental Ophthalmology, April 2013 (224)
|April 25, 2013||Posted by admin under 2013, Abstract, vitreo-retina|
Beta-blockers may reduce anti-VEGF treatment burden
This retrospective case series study included 46 patients with wet AMD treated with bevacizumab injections on a prn regime. Patients treated with systemic beta-adrenergic blocking agents required less intravitreal injections (5.2 vs. 7.9), a statistically significant difference (P= 0.0068, multiple linear regression).
Retina, April 2013 (479)
|April 23, 2013||Posted by admin under 2013, Abstract, vitreo-retina|
This retrospective review of all intravitreal injections performed at the Massachusetts Eye and Ear Infirmary over five years shows an endophthalmitis rate of 0.029 percent per injection, three cases out of 10,208 injections. Bacterial cultures revealed coagulase-negative Staphylococcus species, Staphylococcus epidermidis and one negative culture. All cases were successfully treated with either intravitreal antibiotics and steroids or pars plana vitrectomy. Data also suggest that omission of a sterile drape, eyelid speculum or postinjection antibiotics by several of the treating ophthalmologists did not result in an increased rate of postinjection endophthalmitis.
British Journal of Ophthalmology, April 2013 (149)