Category: cataract

Cataracts From Statins? More Signals Emerge in Analyses

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Cataracts From Statins? More Signals Emerge in Analyses

VANCOUVER, BC — Statin therapy significantly elevates the risk of developing cataracts severe enough to warrant surgery, suggests analyses of two distinct cohorts, one from Canada and another from the US, that add to a hazy landscape of prior studies variously  concluding for or against such a risk for the widely used drugs[1].

For now, the possibility of such a risk from statins and its potential mechanisms should be explored in prospective trials, “especially in light of increased statin use for primary prevention of cardiovascular disease and the importance of acceptable vision in old age, when cardiovascular disease is common,” according to the report, published in the December 2014 issue of the Canadian Journal of Cardiology with lead author Dr Stephanie J Wise (University of British Columbia, Vancouver).

“However, because the relative risk is low and because cataract surgery is (more…) (207)

Non-steroidal Anti-Inflammatory Eyedrops Don’t Prevent CME

AsianOphthalmology Alliance logo Nonsteroidal Anti-Inflammatory Eyedrops Don’t Prevent Cystic Macular Edema, Small Study Finds

NEW YORK (Reuters Health) – The nonsteroidal anti-inflammatory eyedrops ketorolac and nepafenac do not prevent cystoid macular edema after phacoemulsification, researchers from Brazil report.
Most patients exhibit inflammation after cataract surgery that requires treatment with an anti-inflammatory eyedrop, typically a steroid, they write in the British Journal of Ophthalmology, online November 10.

Dr. Patrick Frensel Tzelikis from Brasilia Ophthalmologic Hospital in Brasilia and colleagues evaluated the effects of ophthalmic solutions of ketorolac 0.4% and nepafenac 0.1% in preventing cystic macular edema (assessed by optical coherence tomography (OCT)) after phacoemulsification cataract extraction.

Patients were randomly assigned to receive an artificial tear substitute (n=40), ketorolac 0.4% (n=45) or nepafenac 0.1% (n=41). All patients received prednisolone 1% eyedrops on a (more…) (329)

Experimental Plug Aids Recovery From Cataract Surgery

AsianOphthalmology Alliance logo Experimental Plug Aids Recovery From Cataract Surgery

CHICAGO — A tapered-release dexamethasone punctum plug appears to be a reasonable alternative to medicated eye drops for patients who have undergone cataract surgery, according to early research.

“In clinical use, the sustained release may reduce patient pain,” said Tom Walters, MD, from Texan Eye in Austin. Dr Walters presented the phase 2 study during the cataracts session here at the American Academy of Ophthalmology 2014 Annual Meeting.

The prospective randomized double-masked trial involved 59 patients at 4 sites. The primary end points of the study were the absence of cells in the anterior chamber — a measure of ocular inflammation — and the absence of pain.

Immediately after cataract surgery, patients were randomized; half received the dexamethasone punctum plug and half received a placebo vehicle punctum plug. In this study, (more…) (301)

Intra-cameral moxifloxacin appears safe in cataract surgery : Abstract

AsianOphthalmology Alliance logo Intracameral moxifloxacin appears safe in cataract surgery

This retrospective study evaluated the safety of intracameral moxifloxacin 0.5% (500 mg/0.1 ml) in 244 patients (353 eyes) who underwent uncomplicated cataract surgery. At three months postop, there was minimal anterior chamber reaction, and no significant change was noted in corneal thickness or endothelial cell density.

Philippine Journal of Ophthalmology, January-June 2014 (296)

IOL injector should match corneal incision size

AsianOphthalmology Alliance logo IOL injector should match corneal incision size

Using an experimental model for calculating induced stress on corneal incisions during intraocular lens implantation, researchers compared the nozzles of common injectors using two incision sizes, 2.4- or 2.2-mm. They showed major differences (greater than 38%) between the lowest and highest levels of induced stress when different injectors and different incision sizes were compared. They suggest that better surgical results may be achieved if surgeons match the injector with the incision size. If the surgeon prefers a specific injector system, the incision size should be matched to the size of the injector’s nozzle. 

American Journal of Ophthalmology, July 2014

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Lid scrubbing increases contamination risk during cataract surgery

AsianOphthalmology Alliance logo Lid scrubbing increases contamination risk during cataract surgery

This randomized, controlled, double-masked trial evaluated two preop sterilization techniques: In one group (153 eyes), the lid margin was compressed and scrubbed for 360 degrees five times with a dry sterile cotton-tipped applicator immediately after ocular sterilization and before povidone–iodine irrigation of the conjunctival sac. The second group (153 eyes) had identical sterilization but no lid scrubbing. The rate of positive bacterial culture in liquid in the collecting bag was significantly higher with mechanical compression of the lid margin (P=.001), perhaps due to secretions from the lid margin glands. 

Journal of Cataract & Refractive Surgery, August 2014 (1349)

Multifocal IOLs can significantly reduce central visual field

AsianOphthalmology Alliance logo Multifocal IOLs can significantly reduce central visual field

This is the first study to use Humphrey Visual Field 10-2 testing to compare the effects of multifocal and monofocal IOLs on the central 10 degrees of vision. The multifocal group demonstrated a significant depression in MD, by approximately 2 dB, that did not improve with time or neuroadaptation. The authors suggest multifocal IOLs may be inadvisable in patients who cannot tolerate central visual field reduction, such as those with macular degeneration, retinal pigment epithelium changes or glaucoma. 

American Journal of Ophthalmology, August 2014

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Risk factors for acute postoperative intraocular pressure elevation after phacoemulsification in glaucoma patients

AsianOphthalmology Alliance logo Risk factors for acute postoperative intraocular pressure elevation after phacoemulsification in glaucoma patients

Author(s): Slabaugh M, Bojikian K, Moore D, Chen P
Treatments discussed: acetazolamide

PURPOSE To evaluate the risk factors for and frequency of an acute intraocular pressure (IOP) elevation (spike) after phacoemulsification in patients with glaucoma.

(more…) (2720)

Complications of Glued IOL : Dr Priya Narang

Healio_OSN: BLOG: Complications of glued IOL, by Priya Narang, MS. Read it here: http://ow.ly/rRsOX (912)

Micro-Stent Safe With Cataract Surgery for Glaucoma

AsianOphthalmology Alliance logo Micro-Stent Safe With Cataract Surgery for Glaucoma

The CyPass Micro-Stent procedure for glaucoma can be safely combined with cataract surgery, according to 2-year results from the CYCLE trial. Investigators report that the procedure provided sustained control of intraocular pressure and reduced medication use.

“This procedure is an attempt to have surgeries for glaucoma that are safer and easier for the patient,” said investigator Brian Flowers, MD, from Fort Worth, Texas. “Current surgical treatments for glaucoma are associated with events such as suprachoroidal hemorrhage and bleb-related complications. Microinvasive surgical stenting of the supraciliary space may improve aqueous flow, with fewer complications,” he explained here at the American Academy of Ophthalmology (AAO) 2013 Annual Meeting.

There are 2 main approaches to minimally invasive glaucoma surgery, (more…) (1282)

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